Some of us still intuitively believe that our extensively safeguarded corporate networks are safe from the risks we are exposed to when connecting directly to public Internet. Yet, evidence suggests that most companies now operate with significant persistent malware present in the network. At the same time, malware has also evolved, and we have witnessed a larger proportion of infections being brief with relatively low risk. But, even the seemingly low risk infections may open a pathway or potentially escalate into full-fledged attacks with serious business impact.